Biggest thing is make sure you don't already have something using port 80 and 443 or just go with the other port assignment.
WSUS v6.2 (on Server 2012 R2) doesn't use ports 80 and 443, so this would not likely be relevant. (Unless the configuration had been reverted using WSUSUTIL.)
SSL on WSUS v6.2 would be accessed via port 8531.
Lawrence Garvin, M.S., MCSA, MCITP:EA, MCDBA
SolarWinds Head Geek
Microsoft MVP - Software Packaging, Deployment & Servicing (2005-2014)
My MVP Profile: http://mvp.microsoft.com/en-us/mvp/Lawrence%20R%20Garvin-32101
http://www.solarwinds.com/gotmicrosoft
The views expressed on this post are mine and do not necessarily reflect the views of SolarWinds.